Precision Biologics Development with Octet BLI at Scinai BioServices
Transforming Precision Biologics Development with Octet BLI at Scinai BioServices: Experience the Power of Label-Free Technology
for Unrivaled Biomolecular Interaction Analysis.
At Scinai BioServices, Octet Bio-Layer Interferometry (BLI) technology is a cornerstone of our biologics development and manufacturing workflows. Octet enables rapid, precise, and high-throughput biomolecular analysis, supporting critical stages from early discovery to GMP-ready clinical development.
How Does Octet Work?
Octet BLI measures biomolecular interactions in real time using optical interference on biosensors. Key features include:
Label-free detection: No chemical modification needed, simplifying workflows and preserving sample integrity
Minimal sample consumption: Ideal for early-stage development with limited material
High-throughput capability: Multiple samples analyzed simultaneously, increasing efficiency
Compatibility with crude samples: Can use cell culture supernatants directly without extensive purification
Real-time monitoring: Allows online adjustments and rapid optimization
This combination of features makes Octet BLI a trusted tool for protein quantification, kinetic characterization, and interaction studies across discovery, development, and quality control.
From Early Clone Selection to Clinical Readiness
Octet supports key stages of the biologics development journey:
Upstream: High-throughput screening to identify top-performing protein-producing clones
Downstream: Accurate quantification of specific activity throughout purification steps
Clinical: Half-life determination in serum for pharmacokinetic profiling
Quality Control: Kinetic analysis for batch release and long-term stability
By integrating Octet into these workflows, Scinai ensures efficiency, reproducibility, and reliable data from research to clinical readiness.
Why Octet BLI Technology Matters
Octet BLI is valued by scientists because it simplifies workflows while delivering high-quality, actionable data:
✓ Label-free detection → Simplified workflows
✓ Low sample volume → Preserves valuable material
✓ Crude sample compatibility → Faster turnaround
✓ Real-time monitoring → Smarter optimization
✓ High throughput → Accelerated development
These capabilities allow Scinai to optimize assays, accelerate development, and maintain precision throughout biologics discovery and production.
How We Use Octet at Scinai
At Scinai, we use Octet BLI to:
Perform high-throughput screening of protein-producing clones directly from crude media
Quantify specific activity during purification
Conduct kinetic and pharmacokinetic studies, including serum half-life estimation
Support quality control for batch release and long-term stability
This integrated approach ensures reliable, reproducible, and regulatory-ready results, enabling Scinai to deliver biologics efficiently and confidently.
Octet BLI at Scinai is a powerful, precise, and high-throughput tool that drives efficiency, reliability, and scientific rigor across biologics development—from early discovery through GMP-ready production and clinical evaluation.
A Word from Merav Kamensky, Head of Quality Control and CMC Analytics
“The Octet platform is a critical technology at Scinai, driving efficiency and precision across discovery, development, and quality control.”
Merav Kamensky, Head of Quality Control and CMC Analytics, Scinai BioServices
